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Infliximab-induced seizures in a patient with Crohn's disease: a case report
Zhijie Lv1, Xiaoqi Zhang2, Li Wu3
1Department of Pharmacy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 Qingchun Road, Hangzhou, 310006, Zhejiang, China.
Background:
Infliximab-induced seizures in patients with Crohn's disease are extremely rare and the mechanism of infliximab-induced seizures is unclear.
Case Presentation:
A 60-year-old woman with Crohn's disease experienced infliximab-induced seizures, diagnosed on normal magnetic resonance imaging of the brain. Moreover, the rechallenge with infliximab was positive.
Conclusions:
Neurological assessment and tight clinical monitoring before and during therapy with infliximab should be performed in patients with pre-existing seizure disorders.
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