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A Single-center Retrospective Cohort Study on Cesarean Section under General Anesthesia
Xu Li1, Bi-Ye Wu1,2, Ming-Zhu Zhang1,3
1Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
General anesthesia (GA) for cesarean section (CS) is often chosen due to maternal medical conditions. Higher maternal American Society of Anesthesiologists (ASA) grades and shorter gestation periods are linked to increased ICU admissions and lower Apgar scores in neonates.
Area of Science:
- Anesthesiology
- Obstetrics
- Neonatal Care
Background:
- Neuraxial block is standard for cesarean section (CS).
- General anesthesia (GA) is crucial for urgent/high-risk CS.
- Understanding GA indications and outcomes in CS is vital.
Purpose of the Study:
- To identify reasons for using GA in CS.
- To analyze factors influencing maternal and fetal outcomes under GA for CS.
- To assess the relationship between maternal health status, gestation, and outcomes.
Main Methods:
- Retrospective analysis of 98 CS cases under GA (2014-2016).
- Collected clinical data on maternal status, perioperative information, and outcomes.
- Compared ICU admission rates, hospital stay, and neonatal Apgar scores based on ASA grade, gestational age, and blood loss.
Main Results:
- Internal/surgical diseases (60.2%) were the primary reason for GA in CS.
- Higher ASA grade (III-IV), preterm gestation (<37 weeks), and significant blood loss (>800ml) correlated with higher ICU rates.
- Preterm gestation and higher ASA grade were associated with longer hospital stays and lower neonatal Apgar scores.
Conclusions:
- Maternal medical conditions are the main drivers for GA in CS.
- High maternal ASA grade and preterm gestation are risk factors for adverse maternal and neonatal outcomes following GA for CS.
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