Related Experiment Video
Updated: Nov 8, 2025

An Orthotopic Model of Murine Bladder Cancer
Published on: February 6, 2011
Sarcomatoid urothelial carcinoma of the bladder with osseous metaplasia: bone in urinary bladder
Bharti Varshney1, Gautam Ram Choudhary2, Taruna Yadav3
1Pathology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Abstract:
Sarcomatoid urothelial carcinoma is a rare aggressive malignant neoplasm of the urinary bladder. It usually presents at an advanced stage and thus carries a poor prognosis. These tumours are usually managed with multimodal therapies such as cystectomy and chemotherapy. In the present case, a 72-year-old man presented with gross haematuria and was diagnosed as sarcomatoid urothelial carcinoma with chondrosarcomatous differentiation and extensive stromal osseous metaplasia. The patient was managed with transurethral resection of bladder tumour (TURBT), followed by intravesical chemotherapy. The patient is doing well post 14 months follow-up. Hence, complete TURBT with chemotherapy is also a viable option for patients who prefer to preserve bladder.
Related Concept Videos
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Anatomy of the Genitourinary System II: Bladder and Urethra
Ureters
Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...

