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Related Experiment Video

Updated: Nov 8, 2025

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Explaining Sudden Unexpected Infant Deaths, 2011-2017.

Sharyn E Parks1, Alexa B Erck Lambert2, Fern R Hauck3

  • 1Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia; svp2@cdc.gov.

Pediatrics
|April 28, 2021
PubMed
Summary

Sudden unexpected infant death (SUID) is often linked to unsafe sleep, with most cases unexplained. Further investigation is needed to understand causes and improve prevention strategies for infant mortality.

Keywords:
CDCCDRCenters for Disease Control and PreventionChild Death ReviewDSINAME PanelNFR-CRSNational Association of Medical Examiners’ Panel on Sudden Unexpected Death in PediatricsNational Fatality Review Case Reporting SystemSIDSSUIDdeath scene investigationsudden infant death syndromesudden unexpected infant death

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Area of Science:

  • Pediatrics
  • Public Health
  • Forensic Pathology

Background:

  • Sudden unexpected infant death (SUID) encompasses explained and unexplained infant deaths, with etiology and prevention crucial for understanding.
  • Current death certificate data lacks the detail to differentiate SUID categories or circumstances.
  • The Centers for Disease Control and Prevention (CDC) SUID Case Registry offers a detailed dataset for analysis.

Purpose of the Study:

  • To report SUID rates categorized as explained and unexplained.
  • To describe demographic factors and recent injury or illness history in SUID cases.
  • To analyze the circumstances surrounding SUID, particularly sleep environments.

Main Methods:

  • Utilized the CDC SUID Case Registry, a population-based surveillance system.
  • Data sourced from death certificates, scene investigations, and autopsy reports (2011-2017).
  • Classified SUID cases into explained and unexplained categories using the registry's system and calculated mortality rates.

Main Results:

  • 82% of 4929 SUID cases were unexplained; 72% occurred in unsafe sleep environments.
  • The overall SUID mortality rate was 97.3 per 100,000 live births.
  • Approximately 75% of explained suffocation deaths involved airway obstruction from soft bedding.

Conclusions:

  • Unsafe sleep was prevalent in both explained and unexplained SUID, though only ~20% were classified as explained suffocation.
  • Further investigation of unexplained SUID is vital for generating research hypotheses and identifying at-risk infants.
  • Improving death scene investigation and documentation can enhance understanding of SUID etiology and prevention.