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Cold scissors versus electrosurgery for hysteroscopic adhesiolysis: A meta-analysis
Liuqing Yang1, Ling Wang1,2, Yun Chen1
1Department of TCM Gynecology, Hangzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University.
Medicine
|April 28, 2021
Summary
Hysteroscopic cold scissors are more effective than electrosurgery for treating intrauterine adhesions, significantly reducing recurrence rates and improving outcomes. This method offers a safer and more efficient approach to restoring reproductive health.
Area of Science:
- Reproductive Medicine
- Gynecologic Surgery
- Minimally Invasive Procedures
Background:
- Intrauterine adhesions (IUAs) significantly impair female reproductive health.
- Hysteroscopic adhesiolysis is the primary treatment, with cold scissors and electrosurgery as common methods.
- A definitive consensus on the superior hysteroscopic technique for IUAs remains elusive.
Purpose of the Study:
- To compare the efficacy and safety of hysteroscopic cold scissors versus electrosurgery for treating moderate to severe IUAs.
- To evaluate key outcomes including adhesion recurrence, operative time, blood loss, menstrual flow, and pregnancy rates.
Main Methods:
- A systematic review and meta-analysis of randomized controlled trials and observational studies.
- Comprehensive literature search across major databases (PubMed, EMBASE, MEDLINE, etc.) up to April 2020.
- Data extraction and bias assessment using standardized tools (Cochrane Risk of Bias, Newcastle-Ottawa Scale).
Main Results:
- Hysteroscopic cold scissors demonstrated a significantly lower intrauterine adhesion recurrence rate (OR=0.30, P=.0002).
- Cold scissors also led to shorter operation times (MD=-7.78 min, P<.00001) and reduced intraoperative blood loss (MD=-9.88 mL, P<.00001).
- Improved menstrual flow was observed with cold scissors (OR=4.36, P<.00001), with no significant difference in pregnancy rates.
Conclusions:
- Hysteroscopic cold scissors offer superior efficiency in preventing IUA recurrence compared to electrosurgery.
- This technique is associated with reduced intraoperative blood loss and shorter procedure durations.
- Cold scissors also positively impact menstrual flow, making it a potentially preferable method for IUA treatment.

