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Eosinophilic enteritis with perforation.

H S Walia1, T K Abraham, H K Walia

  • 1Department of Surgery, Amiri Hospital, Kuwait.

Canadian Journal of Surgery. Journal Canadien De Chirurgie
|July 1, 1988
PubMed
Summary
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This case report details a rare instance of eosinophilic granuloma in the gastrointestinal tract leading to free perforation. This finding highlights a potentially unique presentation of gastrointestinal eosinophilic infiltration.

Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Eosinophilic granuloma is a rare condition.
  • Gastrointestinal involvement is uncommon.
  • Perforation is an extremely rare complication.

Observation:

  • A 60-year-old female patient presented with symptoms necessitating laparotomy.
  • During surgery, 100 ml of pus was aspirated.
  • A 42-cm segment of the small intestine was resected due to multiple punched-out ulcers.

Findings:

  • Histopathological examination revealed edematous mucosa and submucosa.
  • The affected tissue showed a significant inflammatory infiltrate.
  • Numerous eosinophils and neutrophils were present, suggesting a localized antigenic reaction.

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Implications:

  • This case represents the first reported instance of eosinophilic granuloma with free perforation in the gastrointestinal tract.
  • It expands the spectrum of known gastrointestinal eosinophilic disorders.
  • Further research may elucidate the specific antigens and mechanisms involved in such presentations.