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Published on: August 27, 2019
Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses
Sung Jae Kim1, Cheongung Kim1, Hee Chun Chung1
1Department of Veterinary Microbiology, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.
Abstract:
Feline calicivirus (FCV) is a highly infectious pathogen in cats and widely distributed worldwide with high genetic variation. Full-length open reading frame 2 of 5 from recently isolated Korean FCV isolates were sequenced and compared with those of global isolates. The results of phylogenetic analysis supported dividing global FCV isolates into two genogroups (type I and II) and demonstrated the presence of genogroup II in Korea, indicating their geographic spread in East Asia. High sequence variations in region E of the FCV isolates emphasizes that a novel vaccine needs to be developed to induce protective immunity against various FCV strains.
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