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Published on: July 4, 2021
[Thrombosis and anatomic variants of intracranial dural venous sinuses]
M Yu Maksimova1, Yu I Dubovitskaya1
1Research Center of Neurology, Moscow, Russia.
Insights
Dural sinus hypoplasia, a common variant, can be mistaken for thrombosis. Understanding these venous anomalies is crucial for accurate diagnosis and effective treatment of cerebral venous thrombosis.
Area of Science:
- Neurology
- Radiology
- Vascular Anatomy
Background:
- Intracranial dural venous sinuses exhibit numerous anatomic variants.
- Sinus aplasia or doubling are considered anomalies, while diameter reduction (hypoplasia) is frequent.
Purpose of the Study:
- To investigate the prevalence of dural sinus hypoplasia in patients with tension-type headaches.
- To assess the relationship between dural sinus hypoplasia and cerebral venous thrombosis.
- To emphasize the importance of differentiating hypoplasia from thrombosis for accurate diagnosis.
Main Methods:
- Neuroimaging study of cerebral veins and venous sinuses.
- Analysis of 103 patients (average age 35±10 years) with tension-type headaches.
- Evaluation of transverse and sigmoid sinus diameters and presence of thrombosis.
Main Results:
- Hypoplasia of transverse and sigmoid sinuses was found in 22.4% of patients.
- A connection between sinus hypoplasia and thrombosis was observed in 10 cases.
- Thrombosis occurred on the side of hypoplasia in 9 patients and on the contralateral side in 1 patient.
Conclusions:
- Dural sinus hypoplasia is a common finding and must be differentiated from thrombosis.
- Accurate diagnosis is essential for timely anticoagulation therapy in cerebral venous thrombosis.
- Understanding venous variants aids in avoiding misdiagnosis and ensures appropriate patient management.
Abstract:
A rather large number of different anatomic variants of intracranial dural venous sinuses are known, and they are found so often that interpreting them only as anomalies is unlikely, except for variations such as sinus aplasia or doubling, which can be attributed to anomalies of the venous system. Diameter reduction (hypoplasia) of the transverse and sigmoid sinuses is observed relatively often. In cases of dural sinuses anomalies, sinuses on the contralateral side are necessarily evaluated as the main source of compensation. When diagnosing dural sinus thrombosis, it is necessary to have a clear idea of the structure of the cerebral venous system, so as not to mistakenly accept hypoplasia or sinus aplasia for thrombosis. Our own experience is based on the results of a neuroimaging study of cerebral veins and venous sinuses in 103 patients (average age 35±10 years) with a tension-type headache. Hypoplasia of the transverse and sigmoid sinuses was detected in 21 (22.4%) cases. In 10 cases (6 men, 4 women), a connection was established between hypoplasia of the dural sinuses and thrombosis. Four patients, presented with hypoplasia of the right transverse and sigmoid sinuses and 6 patients with hypoplasia of the left transverse and sigmoid sinuses. Thrombosis developed on the side of sinus hypoplasia (9 patients) or on the contralateral side (1 patient). Early diagnosis of cerebral venous thrombosis is crucial because the use of anticoagulants reduces the risk of a poor prognosis, severe disability without an additional increase in the risk of brain hematomas progression.
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