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Inducement and Evaluation of a Murine Model of Experimental Myopia
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The global burden of myopia is increasing, impacting 30% of the population and projected to reach 50% by 2050. This rise in myopia and high myopia will increase vision loss and societal costs.

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Area of Science:

  • Ophthalmology
  • Public Health
  • Epidemiology

Background:

  • Myopia prevalence is rising globally, affecting nearly 30% of the population in 2020 and projected to impact 50% by 2050.
  • High myopia prevalence is increasing disproportionately, leading to greater risks of vision loss and complications.

Purpose of the Study:

  • To analyze the impact of myopia on individuals and society.
  • To summarize research on myopia prevalence, pathological manifestations, and associated costs.
  • To review novel approaches for myopia prevention and control.

Main Methods:

  • Literature review synthesizing evidence on myopia prevalence and its consequences.
  • Analysis of direct health expenditures and indirect costs (lost productivity, reduced quality of life).
  • Examination of trends in myopia and high myopia, including pathological manifestations.

Main Results:

  • Myopia and high myopia prevalence are increasing, with a significant rise in high myopia.
  • Future vision loss and complications like myopic macular degeneration are expected to increase.
  • Global costs associated with myopia, including healthcare and lost productivity, are in the billions and projected to rise.

Conclusions:

  • The growing prevalence of myopia and high myopia presents a significant and increasing global health and economic burden.
  • Reduced quality of life and increased healthcare costs are associated with uncorrected myopia, high myopia, and its complications.
  • Further research is needed on the lifelong impact of myopia and the cost-effectiveness of interventions to mitigate its burden.