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Updated: Nov 7, 2025

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Pediatric Flexible Endoscopic Evaluation of Swallowing: Critical Analysis of Implementation and Future Perspectives
Jana Zang1, Julie Cläre Nienstedt2, Jana-Christiane Koseki2
1Department of Voice, Speech and Hearing Disorders, Center for Clinical Neurosciences, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. j.zang@uke.de.
Insights
Pediatric swallowing assessments reveal that underlying conditions significantly increase dysphagia risk. Standardized flexible-endoscopic evaluation of swallowing (FEES) protocols are needed for better data comparison.
Area of Science:
- Pediatric Medicine
- Gastroenterology
- Neurology
Background:
- Pediatric dysphagia presents diagnostic challenges.
- Flexible-endoscopic evaluation of swallowing (FEES) is a key assessment tool.
- Variability in FEES implementation and documentation hinders comparative analysis.
Purpose of the Study:
- To review pediatric FEES data and assess the need for standardized procedures.
- To investigate the relationship between dysphagia and underlying medical conditions in children.
- To evaluate the current implementation and outcomes of pediatric FEES.
Main Methods:
- Retrospective analysis of 152 FEES in 128 children (21 days to 18 years).
- Descriptive analysis of patient demographics, pathologies, and diagnoses.
- Binary logistic regression to identify risk factors for dysphagia.
Main Results:
- Children with underlying diseases had a 13-fold increased chance of dysphagia.
- Genetic syndromes and neurologic disorders were significantly associated with higher dysphagia odds.
- FEES completion rate was high (96.7%), but documentation varied, with missing pathology information.
Conclusions:
- Underlying medical conditions are strong predictors of pediatric dysphagia.
- Standardized protocols and documentation for pediatric FEES are crucial.
- Standardization will improve comparability of epidemiological, assessment, and treatment outcome studies.
Abstract:
This study aimed to critically review pediatric swallowing assessment data to determine the future need for standardized procedures. A retrospective analysis of 152 swallowing examinations in 128 children aged 21 days to 18 years was performed. The children were presented at a university dysphagia center between January 2015 and June 2020 for flexible-endoscopic evaluation of swallowing (FEES). Descriptive analysis was conducted for the sample, swallowing pathologies, diagnosis, and missing values. Using binary logistic regression, the relationship between dysphagia and underlying diseases was investigated. The largest group with a common diagnosis in the cohort were children with genetic syndromes (n = 43). Sixty-nine children were diagnosed with dysphagia and 59 without dysphagia. The non-dysphagic group included 15 patients with a behavioral feeding disorder. The presence of an underlying disease significantly increased the chance of a swallowing problem (OR 13.08, 95% CI 3.66 to 46.65, p = .00). In particular, the categories genetic syndrome (OR 2.60, 95% CI 1.15 to 5.88) and neurologic disorder (OR 4.23, 95% CI 1.31 to 13.69) were associated with higher odds for dysphagia. All pediatric FEES were performed without complications, with a completion rate of 96.7%, and with a broad variability of implementation. Several charts lacked information concerning swallowing pathologies, though. Generally, a more standardized protocol and documentation for pediatric FEES is needed to enable better comparability of studies on epidemiology, assessment, and treatment outcomes in future.
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