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Related Concept Videos

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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The Thyroid Gland01:23

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
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Functions of Thyroid Hormones01:18

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
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Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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Neuromonitoring of recurrent laryngeal nerves in thyroid surgery comparative study of visualisation and electrophysiology methods.

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Morbidity and mortality of parathyroid surgery - a retrospective analysis.

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Related Experiment Video

Updated: Nov 7, 2025

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
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Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

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Morbidity and mortality associated with thyroid surgery - retrospective analysis 19912010.

J Astl, J Plzák, P Laštůvka

    Rozhledy V Chirurgii : Mesicnik Ceskoslovenske Chirurgicke Spolecnosti
    |April 29, 2021
    PubMed
    Summary
    This summary is machine-generated.

    Thyroid surgery is safe, with low mortality (0.007%) and manageable complication rates for recurrent nerve injury and hypoparathyroidism. Multidisciplinary collaboration ensures effective thyroid disorder management and good patient prognosis.

    Keywords:
    complications − recurrent nervehypoparathyroidism − lethalitythyroid surgery

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    Area of Science:

    • Endocrinology
    • Surgical Oncology
    • Otorhinolaryngology

    Background:

    • Rising global incidence of thyroid disorders.
    • Modest increase in mortality from malignant thyroid cancer.
    • Specific mortality rate increases in Czech men and women noted.

    Purpose of the Study:

    • Analyze incidence, morbidity, mortality, complications, and lethality of thyroid surgery.
    • Evaluate surgical outcomes over a 20-year period.
    • Assess risks associated with thyroidectomy.

    Main Methods:

    • Retrospective statistical analysis of 11,005 thyroid procedures (1991-2010).
    • Data collected from two Prague medical institutions.
    • Analysis included patient demographics, diagnoses, and surgical outcomes.

    Main Results:

    • High female to male patient ratio (5.93:1).
    • Recurrent nerve morbidity: 1.37% for benign, 4.5% for malignant conditions.
    • Permanent hypocalcaemia/hypoparathyroidism incidence: 5.4% (based on PTH levels).
    • Perioperative mortality rate: 0.007% (7 cases within 120 hours).
    • Selective neck dissections recommended for tumor treatment.

    Conclusions:

    • Thyroid surgery carries inherent risks but experienced surgeons minimize complications.
    • Low incidence of recurrent nerve and parathyroid gland injuries achieved.
    • Multidisciplinary approach (endocrinologists, oncologists) ensures effective thyroid disorder management and good prognosis.