Related Experiment Video For LOCalizer™
Updated: Nov 7, 2025
Electromagnetic Navigation Transthoracic Nodule Localization for Minimally Invasive Thoracic Surgery
Published on: May 4, 2022
Combined LOCalizer™ and Intraoperative Ultrasound Localization: First Experience in Localization of Non-palpable
Simona Parisi1, Roberto Ruggiero2, Giorgia Gualtieri2
1Department of Advanced Science and Surgery, General, Mini-invasive, Oncological and Obesity Surgery, Luigi Vanvitelli University of Campania, Naples, Italy simona.parisi-sp@libero.it.
Background:
Wire-guided localization is the gold-standard for the detection of non-palpable breast lesions, although with acknowledged limitations. The aim of this study was to evaluate the combined use of LOCalizerr™ (Hologic, Santa Carla, CA, USA), and intraoperative ultrasound (IOUS) for localization and surgery of non-palpable breast cancer.
Patients And Methods:
Patients with non-palpable breast lesions underwent localization procedure with LOCalizer™ and IOUS. After the placement of the marker, eight measures were made to guide the excision. LOCalizerr™ Pencil and IOUS were performed to obtain the distance between the dissection plane and the margins of lesions.
Results:
The procedure was feasible in the five enrolled patients and associated with clear oncological margins in all cases. Moreover, a high satisfaction according to Likert scale for surgeons, radiologists and patients, performing limited and tailored resections, was reported.
Conclusion:
Combining LOCalizerr™ and IOUS is an effective method for locating non-palpable breast cancer, guarantying excellent oncological and cosmetic results.
