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Related Experiment Video

Updated: Nov 7, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
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Dermoscopic Evolution of Pediatric Nevi.

Fatma Pelin Cengiz1, Yaren Yılmaz2, Nazan Emiroglu1

  • 1Department of Dermatoveneorology, Bezmialem Vakif University, Istanbul, Turkey.

Annals of Dermatology
|April 29, 2021
PubMed
Summary

Pediatric nevi commonly enlarge over time, a change not specific to melanoma. This study tracked dermoscopic changes in children’s moles, finding enlargement in 33% of cases.

Keywords:
ChildDermoscopyNevus

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Area of Science:

  • Dermatology
  • Pediatric Medicine
  • Medical Imaging

Background:

  • Pediatric melanoma is rare, but dermoscopy aids in differentiating it from common nevi.
  • Understanding benign nevus evolution is crucial for accurate diagnosis in children.

Purpose of the Study:

  • To investigate the dynamic changes in dermoscopic features of benign nevi in children over a four-year period.
  • To characterize the typical evolution of melanocytic lesions in pediatric populations.

Main Methods:

  • A longitudinal study involving 100 pediatric patients with 504 melanocytic lesions.
  • Serial dermoscopic imaging and photography were conducted over a 4-year follow-up period.
  • Analysis included assessment of dermoscopic patterns and lesion size changes.

Main Results:

  • Homogeneous, globular, and reticular patterns were the most common dermoscopic findings.
  • Dermoscopic pattern changes occurred in 27% of younger children (2-10 years) and 20% of older children (11-16 years).
  • Lesion enlargement was observed in 33.5% of nevi, while 15.5% showed involution and 51% remained stable.

Conclusions:

  • The study challenges the notion that pediatric nevi primarily exhibit globular patterns or a consistent transition to reticular patterns.
  • Nevus enlargement is a frequent occurrence in pediatric populations and should not be solely interpreted as indicative of pediatric melanoma.
  • Dermoscopic surveillance is valuable for tracking benign nevus changes in children.