Preneoplastic lesions of the vulva

The authors, after a short review of the anatomo-clinical and epidemiologic patterns of vulvar preneoplastic lesions (VIN), analyze the emerging data from the most recent Literature. From them they suggest a series of questions about the vulvar neoplasia natural history and the biological precursors of this disease. They foresee that the integration of the results that can be obtained from the advanced studies could succeed in clearing up the neoplastic potentiality of preneoplasic vulvar lesions.