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Updated: Nov 7, 2025

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
Published on: June 4, 2021
Successful removal of an acute deep vein thrombosis by the INARI ClotTriever system
Erina Quinn1, Mary Arndt1, James Capanegro1
1Lake Erie College of Osteopathic Medicine, Bradenton, FL, USA.
Abstract:
Pulmonary embolism is most feared sequela of a proximal deep vein thrombosis (DVT). Currently, first-line DVT treatment is anticoagulation to prevent post-thrombotic sequelae like pedal edema as well as a life threatening pulmonary embolism . Advanced therapy considerations for limb- or life-threatening DVT include catheter-directed thrombolysis and thrombectomy. Thrombectomy is necessary when thrombolytics are contraindicated secondary to increased bleeding risk. The authors present a DVT case treated with the mechanical thrombectomy device, ClotTriever (Inari Medical, Irvine, CA), resulting in the efficient and effective removal of thrombus with near-complete resolution of venous symptoms and prompt hospital discharge.
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