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Related Concept Videos

Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

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Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
281
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

510
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
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Related Experiment Video

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Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
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IBD in pregnancy: recent advances, practical management.

Christian P Selinger1, Catherine Nelson-Piercy2, Aileen Fraser3

  • 1Leeds Gastroenterology Institute, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

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|April 29, 2021
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Summary

High-quality care ensures excellent pregnancy outcomes for women with inflammatory bowel disease (IBD). Maintaining IBD remission is crucial, as medication risks are generally low, outweighing flare risks.

Keywords:
crohn's diseaseulcerative colitis

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Area of Science:

  • Gastroenterology
  • Obstetrics
  • Pharmacology

Background:

  • Inflammatory bowel disease (IBD) presents unique challenges during pregnancy.
  • Many IBD patients lack knowledge regarding pregnancy and reproductive health, leading to voluntary childlessness.
  • Active IBD correlates with adverse pregnancy outcomes like preterm birth and fetal loss.

Purpose of the Study:

  • To review current evidence and recommendations for managing pregnant women with IBD.
  • To offer clinical guidance for healthcare providers caring for IBD patients during pregnancy.
  • To address patient knowledge gaps and concerns about IBD and pregnancy.

Main Methods:

  • Comprehensive review of existing literature and clinical guidelines.
  • Analysis of risks associated with IBD activity versus medication use during pregnancy.
  • Evaluation of delivery modes and breastfeeding in the context of IBD management.

Main Results:

  • Excellent pregnancy outcomes are achievable with high-quality care.
  • Maintaining IBD remission is paramount; risks of medication are generally low, except for methotrexate and tofacitinib.
  • Most women with IBD can have normal pregnancies and vaginal deliveries.

Conclusions:

  • Proactive management and maintenance of IBD remission are key for successful pregnancies.
  • Active perianal Crohn's disease and ileal pouch surgery are specific indications for cesarean section.
  • Breastfeeding is encouraged, with minimal risk from most IBD medications.