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Allergen detection and analysis in Eastern Taiwan area.

Chia-Jung Chen1, Yu-Hsien Liu2, Teng-Yi Lin2

  • 1Department of Nursing, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.

Tzu Chi Medical Journal
|April 29, 2021
PubMed
Summary

Children show higher cow milk allergy sensitization, while adults exhibit increased shrimp allergy sensitization in eastern Taiwan. This study highlights age-related differences in allergen profiles.

Keywords:
Allergic diseaseIgESpecific IgE

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Area of Science:

  • Allergy and Immunology
  • Epidemiology
  • Environmental Health

Background:

  • Allergen sensitization profiles can vary based on environmental factors, dietary habits, and age.
  • Understanding these variations is crucial for targeted allergy prevention and management strategies.

Purpose of the Study:

  • To investigate and compare the distinct allergen sensitization profiles across different age groups in eastern Taiwan.
  • To identify age-specific patterns in food and aeroallergen sensitization.

Main Methods:

  • Analysis of 15,455 allergic patients undergoing allergen sensitization testing.
  • Utilized Phadiatop (atopy screen) and Pharmacia CAP System methods.
  • Comparison of sensitization rates between pediatric and adult populations.

Main Results:

  • Children exhibited significantly higher food and aeroallergen sensitization rates compared to adults (44.0% vs. 9.9% and 61.9% vs. 52.2%, respectively).
  • Cow milk allergen-specific sensitization was notably higher in children (32.9%) than adults (5.8%).
  • Adults demonstrated a higher sensitization rate to shrimp (33.6%) compared to children (24.8%).

Conclusions:

  • Children in eastern Taiwan show a greater prevalence of cow milk allergy sensitization.
  • Adults in the region are more frequently sensitized to shrimp allergens.
  • Age is a significant factor influencing allergen sensitization patterns, necessitating age-specific approaches to allergy care.