Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Work-Related Musculoskeletal Symptoms in Surgeons Performing Total Knee Arthroplasty: An Exploratory Cross-Sectional Survey.

Journal of clinical medicine·2026
Same author

Kinematic Alignment in Total Knee Arthroplasty of Varus Knees Minimises Distal Ankle Compensatory Changes Compared with Mechanical Alignment.

Journal of clinical medicine·2026
Same author

Association of Baseline Femoral Trochlear T2* Mapping with Clinical Response to Platelet-Rich Plasma in Patellofemoral Chondropathy: A Retrospective Exploratory Study.

Journal of clinical medicine·2026
Same author

Early Treatment of Developmental Trochlear Dysplasia With Modified Pavlik Harness: A Proof-of-Concept Pilot Study.

Journal of pediatric orthopedics·2026
Same author

Sensitivity to measurement errors in the CPAK classification may affect the accuracy of coronal knee alignment classification.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2026
Same author

Redefining coronal knee alignment: A population-specific centre-of-mass framework beyond coronal plane alignment of the knee thresholds.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2026

Related Experiment Video

Updated: Nov 7, 2025

Author Spotlight: Segmentation and VR for Advanced Neurovascular Interventions
06:18

Author Spotlight: Segmentation and VR for Advanced Neurovascular Interventions

Published on: April 5, 2024

1.3K

Patient-Specific Instrumentation Accuracy Evaluated with 3D Virtual Models.

Vicente J León-Muñoz1, Andrea Parrinello2, Silvio Manca3

  • 1Department of Orthopaedic Surgery and Traumatology, Hospital Clínico Universitario Virgen de la Arrixaca, Ctra. Madrid-Cartagena, s/n, 30120 Murcia, Spain.

Journal of Clinical Medicine
|April 30, 2021
PubMed
Summary

Patient-specific instrumentation (PSI) for total knee arthroplasty (TKA) showed minor angular alignment differences compared to planning. These small discrepancies did not significantly impact patient-reported outcomes in this study.

Keywords:
alignmentkneepatient matched technologythree-dimensional analysistotal knee arthroplastytotal knee replacement

More Related Videos

Measuring the Complete-arch Distortion of an Optical Dental Impression
06:51

Measuring the Complete-arch Distortion of an Optical Dental Impression

Published on: May 30, 2019

7.8K
Creation of Patient-Specific Silicone Cardiac Models with Applications in Pre-surgical Plans and Hands-on Training
09:15

Creation of Patient-Specific Silicone Cardiac Models with Applications in Pre-surgical Plans and Hands-on Training

Published on: February 10, 2022

3.9K

Related Experiment Videos

Last Updated: Nov 7, 2025

Author Spotlight: Segmentation and VR for Advanced Neurovascular Interventions
06:18

Author Spotlight: Segmentation and VR for Advanced Neurovascular Interventions

Published on: April 5, 2024

1.3K
Measuring the Complete-arch Distortion of an Optical Dental Impression
06:51

Measuring the Complete-arch Distortion of an Optical Dental Impression

Published on: May 30, 2019

7.8K
Creation of Patient-Specific Silicone Cardiac Models with Applications in Pre-surgical Plans and Hands-on Training
09:15

Creation of Patient-Specific Silicone Cardiac Models with Applications in Pre-surgical Plans and Hands-on Training

Published on: February 10, 2022

3.9K

Area of Science:

  • Orthopedic Surgery
  • Biomechanical Engineering
  • Medical Imaging

Background:

  • Knee replacement surgery has advanced, but accurate alignment remains a challenge.
  • Patient-specific instrumentation (PSI) aims to improve component placement accuracy in total knee arthroplasty (TKA).
  • Existing evidence on PSI's effectiveness in achieving desired alignment is inconclusive.

Purpose of the Study:

  • To evaluate the three-dimensional accuracy of a PSI system in TKA.
  • To compare post-operative alignment with pre-operative planning using computed tomography (CT) data.
  • To analyze the relationship between alignment accuracy and patient-reported outcomes.

Main Methods:

  • Retrospective analysis of 35 TKAs using a PSI system.
  • 3D virtual models were created from post-operative CT scans.
  • Angular discrepancies between planned and achieved alignment were measured for multiple parameters (hip-knee-ankle angle, tibial slope, etc.).

Main Results:

  • Statistically significant differences were found between planned and achieved angular alignment values.
  • Mean discrepancies ranged from 0.64° to 2.28° across different parameters.
  • No significant correlation was observed between alignment variables and patient-reported outcomes.

Conclusions:

  • The evaluated PSI system demonstrated statistically significant, yet clinically minor, deviations in 3D alignment.
  • These small alignment discrepancies did not negatively influence patient-reported outcomes following TKA.
  • Further research may be needed to fully elucidate the clinical impact of PSI in TKA alignment.