Related Experiment Videos
Allopurinol kinetics after massive overdosage
R E Ferner1, H A Simmonds, D N Bateman
1Regional Clinical Pharmacology Unit, Freeman Hospital, Newcastle upon Tyne, UK.
Human Toxicology
|May 1, 1988
Abstract:
A 15-year-old girl with normal renal function took 75 tablets of allopurinol 300 mg. She did not suffer any ill-effects. Samples obtained over 84 h showed prolonged elimination of allopurinol, with a half-life of 3.6 h, and oxipurinol, with a half-life of 26 h.