Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

2.4K
Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...
2.4K
ATP and Macromolecule Synthesis01:28

ATP and Macromolecule Synthesis

6.4K
Biological macromolecules are organic compounds, predominantly composed of carbon atoms. The carbon atoms are covalently bonded with hydrogen, oxygen, nitrogen, and other minor elements. There are four major biological macromolecule classes: carbohydrates, lipids, proteins, and nucleic acids.
Most macromolecules are composed of single subunits, or building blocks, called monomers. The monomers combine with each other using covalent bonds to form larger molecules known as polymers.
Conversion of...
6.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Temperature-Dependent Conformational Dynamics of Substrate Entrance Loops in β-Glucosidase: Insights from Molecular Dynamics Simulations.

International journal of molecular sciences·2026
Same author

Temperature-Dependent Active-Site Rearrangements of PETaseSM14: Insights from Molecular Dynamics Simulations.

International journal of molecular sciences·2026
Same author

Evaluation of AI-Predicted GH11 Xylanase Models Against a Previously Unreported Experimental Structure: Implications for Conformational Accuracy and Ligand Binding.

International journal of molecular sciences·2026
Same author

Special Issue "Structural Dynamics of Macromolecules".

International journal of molecular sciences·2026
Same author

Structural flexibility of the nicotinamide group of NADH in butanol dehydrogenase YqdH from Fusobacterium nucleatum.

PloS one·2025
Same author

Structure-Based Understanding of Cu<sup>2+</sup> Coordination in Fluorescent Proteins for Metal Biosensor Applications-A Review.

Biosensors·2025

Related Experiment Video

Updated: Nov 7, 2025

Analyzing Melts and Fluids from Ab Initio Molecular Dynamics Simulations with the UMD Package
06:37

Analyzing Melts and Fluids from Ab Initio Molecular Dynamics Simulations with the UMD Package

Published on: September 17, 2021

4.8K

Molecular Dynamics-From Small Molecules to Macromolecules.

Ki Hyun Nam1

  • 1Department of Life Science, Pohang University of Science and Technology, Pohang 37673, Korea.

International Journal of Molecular Sciences
|April 30, 2021
PubMed
Summary

Understanding molecular dynamics is crucial for all molecular systems. Studying molecular structure and dynamics reveals function, properties, and mechanisms, aiding drug and material development.

Keywords:
conformational changemolecular dynamicsstructural changetime-resolved

More Related Videos

Author Spotlight: Streamlining Visual Dynamics to Simplify Molecular Dynamics Simulations Using Gromacs
05:00

Author Spotlight: Streamlining Visual Dynamics to Simplify Molecular Dynamics Simulations Using Gromacs

Published on: August 9, 2024

1.6K
Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches
07:31

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

2.7K

Related Experiment Videos

Last Updated: Nov 7, 2025

Analyzing Melts and Fluids from Ab Initio Molecular Dynamics Simulations with the UMD Package
06:37

Analyzing Melts and Fluids from Ab Initio Molecular Dynamics Simulations with the UMD Package

Published on: September 17, 2021

4.8K
Author Spotlight: Streamlining Visual Dynamics to Simplify Molecular Dynamics Simulations Using Gromacs
05:00

Author Spotlight: Streamlining Visual Dynamics to Simplify Molecular Dynamics Simulations Using Gromacs

Published on: August 9, 2024

1.6K
Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches
07:31

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

2.7K

Area of Science:

  • Biophysics
  • Physical Chemistry
  • Computational Biology

Background:

  • Molecular systems exhibit unique characteristics dependent on their environment and temporal state.
  • Accurate comprehension of molecular functions necessitates detailed studies of their structure and dynamics.

Discussion:

  • Molecular dynamics studies are essential for understanding molecular behavior.
  • Techniques like spectroscopy, structure determination, and computational analysis provide functional insights.
  • These methods capture molecular information at specific times and environmental conditions.

Key Insights:

  • Molecular dynamics reveals intrinsic properties and mechanisms of action.
  • Insights gained are applicable to diverse industrial sectors, including pharmaceuticals and materials science.
  • Understanding molecular motion across various timescales is critical.

Outlook:

  • Further exploration of molecular dynamics will drive innovation in drug discovery and material design.
  • Advanced analytical techniques will enhance the precision of molecular behavior studies.
  • Interdisciplinary approaches integrating computational and experimental methods will be key.