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Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis
Manuel Toledano-Osorio1,2, Manuel Toledano1, Francisco Javier Manzano-Moreno3,4
1Colegio Máximo de Cartuja s/n, Faculty of Dentistry, University of Granada, 18071 Granada, Spain.
Polymers
|April 30, 2021
Summary
Guided bone regeneration (GBR) using polymeric membranes effectively augments horizontal bone, averaging 3.95 mm gain. This predictable technique facilitates successful dental implant placement after tooth loss.
Area of Science:
- Dental Implantology
- Periodontology
- Regenerative Medicine
Background:
- Alveolar bone resorption post-tooth extraction limits dental implant feasibility.
- Bone regenerative procedures are often necessary to restore bone volume.
- Horizontal bone augmentation is crucial for predictable implant placement.
Purpose of the Study:
- To systematically review and meta-analyze the efficacy of guided bone regeneration (GBR) using polymeric membranes for horizontal bone augmentation.
- To assess the predictability and outcomes of GBR in preparing alveolar ridges for dental implants.
Main Methods:
- Systematic review and meta-analysis of randomized controlled trials and observational studies.
- Searches conducted in MEDLINE (PubMed), Embase, and Cochrane Oral Health.
- Weighted means calculated; random-effects model used due to high heterogeneity (I²=99%).
Main Results:
- Mean horizontal bone gain was 3.95 mm (95% CI: 3.19–4.70 mm).
- High heterogeneity observed (I²=99%, p < 0.001), necessitating a random-effects model.
- Complication rate was 8.4%, with membrane exposure being the most common issue.
Conclusions:
- Guided bone regeneration (GBR) with polymeric membranes is a predictable method for horizontal bone augmentation.
- This technique effectively increases bone volume, enabling subsequent dental implant placement.
- GBR offers a viable solution for managing alveolar ridge defects.
