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Dysautonomia in a cat.

D D Canton1, N J Sharp, G D Aguirre

  • 1Department of Surgery, Veterinary Medical Teaching Hospital, University of California, Davis 95616.

Journal of the American Veterinary Medical Association
|May 1, 1988
PubMed
Summary
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A feline diagnosed with autonomic dysfunction experienced severe gastrointestinal and ocular issues. Nutritional support via parenteral and nasogastric feeding was successful, and an ocular pharmacologic study aided diagnosis.

Area of Science:

  • Veterinary Medicine
  • Animal Neurology
  • Feline Health

Background:

  • Autonomic dysfunction, or dysautonomia, is a recognized neurological disorder affecting cats.
  • Early diagnosis and management are crucial for improving outcomes in affected animals.
  • This condition presents with a variety of clinical signs affecting multiple organ systems.

Observation:

  • A 2.5-year-old domestic shorthair cat presented with anorexia, depression, constipation, weight loss, and regurgitation.
  • Physical examination revealed dehydration, cachexia, bradycardia, bilateral unresponsive mydriasis, prolapsed nictitating membranes, and urinary bladder atony.
  • Thoracic radiography identified megaesophagus, indicating impaired esophageal motility and delayed gastric emptying.

Findings:

  • Nutritional support was successfully provided through total parenteral nutrition and nasogastric tube feeding.

Related Experiment Videos

  • An ocular pharmacologic study confirmed complete autonomic denervation of the eye, explaining the mydriasis and nictitating membrane prolapse.
  • The diagnostic approach using autonomic-stimulating agents proved effective in identifying feline dysautonomia.
  • Implications:

    • Topical autonomic-stimulating agents can be a valuable diagnostic tool for feline dysautonomia.
    • Effective nutritional management strategies are essential for treating cats with autonomic dysfunction.
    • This case highlights the potential for increased prevalence of feline dysautonomia in the United States.