Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Methods for Studying Drug Absorption: In vitro

Methods for Studying Drug Absorption: In vitro

In vitro experiments are crucial for understanding the transport and absorption of drugs through biological materials. These studies employ varied methods such as the diffusion cell method, the everted sac technique, and the everted ring technique.
The diffusion cell method uses a two-compartment cell, including a donor compartment with the drug solution, which simulates the environment where the drug is applied, and a receptor compartment with a buffer solution, which simulates the environment...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Target Capture Sequencing Provides Insights Into Hybridogenetic Water Frogs.

Ecology and evolution·2026

Same author

Methane emission from shuttle tankers during standard operations on an oil platform during oil loading.

Environmental science. Processes & impacts·2026

Same author

Five Hidden Species in a Widespread European Vertebrate: Disentangling the Alpine Newt Cryptic Species Complex Through Genomic Phylogeography.

Molecular ecology·2026

Same author

Effect of Supplementing Milk Replacer with <i>Boswellia serrata</i> Resin on Growth Performance, Serum Biochemical Profile, and Meat Quality of Suckling Lambs.

Animals : an open access journal from MDPI·2026

Same author

Unlocking Demography: Developing an eDNA-Based Toolkit to Measure Sex Ratios From Populations.

Molecular ecology resources·2025

Same author

NewtCap: An Efficient Target Capture Approach to Boost Genomic Studies in Salamandridae (True Salamanders and Newts).

Ecology and evolution·2025

Search research articles

Related Experiment Video

Updated: Nov 7, 2025

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Published on: August 23, 2019

An Illustrative Analysis of Atypical Gas Production Profiles Obtained from In Vitro Digestibility Studies Using Fecal

Mewa S Dhanoa¹, Secundino López^2,3, Christopher D Powell¹

¹Department of Animal BioSci.s, University of Guelph, Guelph, ON N1G 2W1, Canada.

Animals : an Open Access Journal From MDPI

|April 30, 2021

Summary

This study addresses complex gas production profiles often seen with fecal inoculum. Numerical modeling using the Mitscherlich equation helps analyze these atypical trends for better understanding.

Keywords:

Mitscherlich equation atypical profiles equivalent profile construction feedstuff evaluation gas production technique numerical modeling

More Related Videos

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Published on: February 15, 2019

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

Related Experiment Videos

Last Updated: Nov 7, 2025

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Published on: August 23, 2019

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Published on: February 15, 2019

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

Area of Science:

Biotechnology
Microbial Fermentation Analysis

Background:

Standard gas production profiles are typically monophasic and monotonically increasing.
Atypical profiles with multiple phases or extraneous features complicate standard modeling.

Purpose of the Study:

To analyze atypical gas production profiles obtained using fecal inoculum.
To explore numerical modeling techniques for reconstructing complex gas production trends.

Main Methods:

Extensions of the Mitscherlich equation were investigated.
A numerical modeling approach based on the Mitscherlich equation was developed.
This method uses smoothed data for relative rate estimation and raw data for lag time.

Main Results:

The proposed numerical modeling reconstructs atypical profiles into equivalent growth-like trends.
The methodology effectively handles multiple phases and extraneous features in gas production data.
Mitscherlich equation extensions provide alternative analytical approaches.

Conclusions:

Numerical modeling offers a robust method for analyzing complex gas production profiles from fecal inoculum.
This approach facilitates the application of growth modeling to challenging datasets.
The study enhances the understanding and analysis of microbial fermentation dynamics.