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Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...

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Updated: Jun 26, 2026

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Toxoplasmic Lymphadenitis Presenting as a Tiny Neck Tumor.

Shih-Lung Chen1,2, Jim-Ray Chen2,3, Shih-Wei Yang2,4

  • 1Department of Otolaryngology & Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou 333, Taiwan.

Healthcare (Basel, Switzerland)
|April 30, 2021
PubMed
Summary

Toxoplasmic lymphadenitis (TL), a global zoonosis, can present as a neck mass. Ultrasound-guided fine needle aspiration cytology (US-guided FNAC) is a valuable first-line diagnostic tool for suspected cases.

Keywords:
fine needle aspiration cytologyhead and necktoxoplasmic lymphadenitisultrasound

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Area of Science:

  • Infectious Diseases
  • Parasitology
  • Oncology

Background:

  • Toxoplasmic lymphadenitis (TL) is a common worldwide zoonotic infection caused by *Toxoplasma gondii*.
  • It frequently affects lymph nodes, particularly in the head and neck region.
  • Diagnosis relies on a combination of clinical presentation, imaging, serology, and histopathology.

Observation:

  • A case of a 51-year-old female presenting with a rapidly growing left posterior neck mass is described.
  • The mass was evaluated using ultrasound (US).
  • Ultrasound-guided fine needle aspiration cytology (US-guided FNAC) was performed for diagnosis.

Findings:

  • Histopathological examination and serological tests confirmed the diagnosis of TL.
  • US-guided FNAC provided crucial diagnostic information.
  • En bloc resection of the affected lymph node was performed.

Implications:

  • US-guided FNAC is proposed as a primary diagnostic method for small neck masses.
  • Early and accurate diagnosis of TL can guide appropriate treatment strategies.
  • This case highlights the utility of minimally invasive techniques in diagnosing parasitic infections.