Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A mouthpiece face mask for the exercising dog.

J Ampil1, J I Carlin, R L Johnson

  • 1Department of Internal Medicine, University of Texas Health Science Center, Dallas 75235.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|May 1, 1988
PubMed
Summary

Researchers developed a new rebreathing mask for dogs to measure lung volumes, cardiac output, and CO diffusing capacity during exercise. This modified, lightweight mask is custom-fitted, reducing anesthesia time and improving comfort for accurate physiological measurements.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Relationship between water repellency and native and petroleum-derived organic carbon in soils.

Journal of environmental quality·2003
Same author

Pro-Leu-glycinamide and its peptidomimetic, PAOPA, attenuate haloperidol induced vacuous chewing movements in rat: A model of human tardive dyskinesia.

Peptides·2003
Same author

Phylogenetics of freshwater black basses (Centrarchidae: Micropterus) inferred from restriction endonuclease analysis of mitochondrial DNA.

Biochemical genetics·2002
Same author

Pulmonary membrane diffusing capacity and capillary blood volume measured during exercise from nitric oxide uptake.

Chest·2001
Same author

Sharper images by focusing soft X-rays with photon sieves.

Nature·2001
Same author

Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function.

Molecular and cellular biology·2001

Area of Science:

  • Physiology
  • Veterinary Medicine
  • Respiratory Research

Background:

  • Accurate measurement of cardiopulmonary function in exercising animals is crucial for research.
  • Existing methods for measuring lung volumes, cardiac output, and diffusing capacity in awake, exercising dogs are often invasive or cumbersome.
  • A need exists for a non-invasive, reliable method adaptable to canine physiology.

Purpose of the Study:

  • To develop and validate a modified low-dead-space rebreathing mask for measuring lung volumes, cardiac output, and carbon monoxide (CO) diffusing capacity in awake exercising dogs.
  • To simplify the fabrication and fitting process of the mask, reducing the need for extensive anesthesia.
  • To improve the comfort and tolerability of the mask during canine exercise studies.

Main Methods:

Related Experiment Videos

  • Adaptation and modification of the Montefusco et al. low-dead-space mask.
  • Simplification of fabrication using prefabricatable parts for custom fitting.
  • Weight reduction of the mask for improved exercise tolerance.
  • Validation of mask leak-tightness using helium (He) rebreathing to achieve gas equilibration.
  • Preliminary measurements of lung volumes, acetylene (C2H2)-based cardiac output, and CO diffusing capacity during exercise.

Main Results:

  • A simplified, custom-fitted, low-dead-space rebreathing mask was successfully developed for dogs.
  • The modified mask design reduces anesthesia time and is more tolerable during exercise.
  • Leak-tightness of the mask was validated using helium equilibration.
  • Preliminary data on lung volumes, cardiac output, and CO diffusing capacity in exercising dogs were obtained.

Conclusions:

  • The modified rebreathing mask provides a practical and validated method for assessing cardiopulmonary function in awake exercising dogs.
  • This technique facilitates non-invasive measurements of key physiological parameters, advancing respiratory and cardiovascular research in canines.
  • The improved mask design enhances the feasibility of conducting complex physiological studies in exercising animals.