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Hypothalamic GHR-SIRT1 Axis in Fasting.

Juliana Bezerra Medeiros de Lima1, Chidera Ubah1, Lucas Kniess Debarba1

  • 1Department of Biological Sciences, Integrative Biosciences Center (IBio), Wayne State University, Detroit, Michigan, MI 48202, USA.

Cells
|April 30, 2021
PubMed
Summary

Growth hormone receptor (GHR) signaling and Sirtuin 1 (SIRT1) interact in the hypothalamus to regulate fasting responses. GHR deletion in AgRP neurons impacts SIRT1

Keywords:
Sirtuin 1arcuate nucleusgrowth hormone axisgrowth hormone receptorhypothalamus

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