A Study on Hematopoietic Stem Cell Donation Volunteer Retention between Swab Sampling Approach and Blood Sampling
Ke Yan1,2,3, Gang Zhang4, Guoqiang Zhao4
1Department of Health Policy and Management, School of Public Health, Fudan University, Shanghai 200032, China.
Summary
Hematopoietic stem cell donation (HSCD) volunteer retention is a global challenge. This study found that sampling methods and demographics significantly impact HSCD volunteer retention, with swab sampling showing better results in younger individuals.
Area of Science:
- * Hematology and Transplant Immunology
- * Public Health and Donor Management
Background:
- * Significant global loss of hematopoietic stem cell donation (HSCD) volunteers poses a challenge to transplant programs.
- * Understanding factors influencing volunteer retention is crucial for maintaining donor registries.
Purpose of the Study:
- * To analyze volunteer retention characteristics based on swab versus blood sampling approaches.
- * To identify demographic factors associated with volunteer retention in HSCD programs.
Main Methods:
- * Telephone follow-up survey of 18,963 volunteers from the Shanghai Bone Marrow Donation Program.
- * Analysis of volunteer retention using multiple logistic regression.
- * Visualization of retention trends using forest plots.
Main Results:
- * Severe volunteer loss observed, with only 32.37% of volunteers successfully contacted.
- * Volunteer retention is influenced by sampling methods and demographic characteristics.
- * Swab sampling showed better retention among young individuals and technicians; blood sampling had lower retention among public officials and workers.
Conclusions:
- * Enhancing contact channels, frequency, and volunteer education is vital for improving HSCD volunteer stability.
- * Tailoring strategies based on demographic profiles and sampling methods can optimize donor retention.


