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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

109
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

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Overview
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Tissue Transplantation01:24

Tissue Transplantation

675
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

125
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Measurement of BK-polyomavirus Non-Coding Control Region Driven Transcriptional Activity Via Flow Cytometry
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BK Virus and Transplantation.

Carla Prezioso1,2, Valeria Pietropaolo1

  • 1Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.

Viruses
|April 30, 2021
PubMed
Summary

This special issue explores BK virus (BKV) diseases in transplant recipients. Further research is needed to clarify BKV-associated complications and improve patient outcomes in transplantation settings.

Area of Science:

  • Nephrology
  • Virology
  • Immunology

Background:

  • BK virus (BKV) is a common polyomavirus that can cause significant complications in organ transplant recipients.

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  • BKV-associated nephropathy (BKVAN) is a major cause of graft loss in kidney transplant patients.
  • The pathogenesis and clinical management of BKV infections in the context of transplantation remain areas of active investigation.