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Published on: January 12, 2024
Role of Oral Antioxidant Supplementation in the Current Management of Diabetic Retinopathy
Enrique Antonio Alfonso-Muñoz1, Raquel Burggraaf-Sánchez de Las Matas2, Jorge Mataix Boronat1
1FISABIO-Oftalmología Médica (FOM), Vitreoretinal Unit, 46015 Valencia, Spain.
Abstract:
Oxidative stress has been postulated as an underlying pathophysiologic mechanism of diabetic retinopathy (DR), the main cause of avoidable blindness in working-aged people. This review addressed the current daily clinical practice of DR and the role of antioxidants in this practice. A systematic review of the studies on antioxidant supplementation in DR patients was presented. Fifteen studies accomplished the inclusion criteria. The analysis of these studies concluded that antioxidant supplementation has a IIB level of recommendation in adult Type 1 and Type 2 diabetes mellitus subjects without retinopathy or mild-to-moderate nonproliferative DR without diabetic macular oedema as a complementary therapy together with standard medical care.
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