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Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials
Published on: March 9, 2017
Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design
Rui Huang1, David C Luther1, Xianzhi Zhang1
1Department of Chemistry, University of Massachusetts Amherst, 710 N. Pleasant St., Amherst, MA 01003, USA.
Abstract:
Nanoparticles (NPs) provide multipurpose platforms for a wide range of biological applications. These applications are enabled through molecular design of surface coverages, modulating NP interactions with biosystems. In this review, we highlight approaches to functionalize nanoparticles with "small" organic ligands (Mw < 1000), providing insight into how organic synthesis can be used to engineer NPs for nanobiology and nanomedicine.
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