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Updated: Nov 7, 2025

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Preliminary In Vitro Study of Fluoride Release from Selected Ormocer Materials.

Piotr Kosior1, Maciej Dobrzynski2, Aneta Zakrzewska3

  • 1Department of Conservative Dentistry with Endodontics, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.

Materials (Basel, Switzerland)
|April 30, 2021
PubMed
Summary

This study measured long-term fluoride ion release from ormocer materials in simulated oral environments. Admira Seal showed the highest release in deionized water, while Admira Flow released the most fluoride in saline solution over 14 weeks.

Keywords:
fluoride ion releasefluoride rechargeormocer materials

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Area of Science:

  • Dental Materials Science
  • Biomaterials Research
  • Polymer Chemistry

Background:

  • Ormocer materials are used in dental restorations.
  • Fluoride release from dental materials is crucial for caries prevention.
  • Understanding long-term ion release is essential for material efficacy.

Purpose of the Study:

  • To evaluate the long-term in vitro fluoride ion release from three ormocer materials: Admira (A), Admira Flow (AF), and Admira Seal (AS).
  • To compare fluoride release into deionized water and a saline solution, simulating oral conditions, over a 14-week period.

Main Methods:

  • In vitro study measuring fluoride ion release over 14 weeks.
  • Materials tested: Admira (A), Admira Flow (AF), Admira Seal (AS).
  • Release media: 0.9% NaCl (saline solution) and deionized water.
  • Measurement intervals: 1, 3 hours, 1, 2, 3 days, weekly for 14 weeks.

Main Results:

  • All tested ormocer materials exhibited a constant fluoride ion release.
  • Highest cumulative fluoride release into deionized water: Admira Seal (23.95 μg/mm²).
  • Highest cumulative fluoride release into saline solution: Admira Flow (8.08 μg/mm²), with the highest initial release after 1 hour.

Conclusions:

  • Ormocer materials demonstrate sustained fluoride ion release in simulated oral environments.
  • Admira Flow and Admira Seal show significant fluoride release potential, with varying performance in different media.
  • The choice of ormocer material may influence the extent and rate of fluoride delivery in the oral cavity.