The structure of a virus-encoded nucleosome

Marco Igor Valencia-Sánchez1, Stephen Abini-Agbomson1, Miao Wang1

  • 1Skirball Institute of Biomolecular Medicine, Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.

Summary

Marseillevirus histones, Hβ-Hα and Hδ-Hγ, mimic eukaryotic histones H2B-H2A and H4-H3. These viral proteins form nucleosome-like structures, organizing viral DNA similarly to eukaryotic chromatin.

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