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Updated: Nov 7, 2025

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Severe Shivering as an Adverse Effect of Regadenoson Myocardial Perfusion Imaging
Tanjeev Ahmad1, Juan Linares2,1,3, Damian N Valencia2,1,3
1Department of Internal Medicine, Division of Cardiovascular Medicine, Boonshoft School of Medicine, Wright State University, Dayton, USA.
Abstract:
Regadenoson myocardial perfusion imaging (MPI) is a widely used screening study for patients with an intermediate pretest probability of coronary artery disease (CAD). Via selective agonism of the adenosine A2A receptor, regadenoson can induce coronary steal, revealing stenotic vessel territory through transient ischemia. Common side effects of this medication include chest pain, shortness of breath, nausea, vomiting, atrioventricular block, seizure, and allergic reactions. Here we present a case of severe shivering and chest tightness after the administration of regadenoson, along with a physiologic explanation and treatment.
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