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Clostridial Mycotic Aneurysm Leading to Emphysematous Aortitis
Thomas G Ng1, Usha Trivedi1, Kajol Shah1
1Internal Medicine, Rutgers University, Newark, USA.
Abstract:
Mycotic aneurysms account for less than 5% of all aneurysms of the aorta, with most cases linked to infection with either Staphylococcus or Salmonella species. Emphysematous aortitis is a rare consequence of mycotic aneurysms and is associated with high morbidity and mortality. It typically occurs from infection superimposed on already damaged endothelium, which is commonly seen in conditions such as atherosclerosis. This report discusses the presentation and relevant imaging findings of a unique case of emphysematous aortitis from Clostridial infection of the thoracic aorta. The patient was a 66-year-old male with a past medical history of end-stage renal disease, arteriovenous fistula for dialysis, hypertension, and diabetes, who presented with tachycardia and tachypnea. Computed tomography of the chest showed inflammatory changes of the thoracic aorta with gas bubbles along the aortic wall, and post-mortem aortic tissue cultures were positive for Clostridium innocuum. Although emphysematous aortitis is rare, the radiographic findings are strikingly characteristic and should prompt immediate and aggressive management.
Insights
This case report details a rare instance of emphysematous aortitis caused by Clostridial infection. Characteristic imaging findings highlight the need for prompt management of this severe aortic condition.
Area of Science:
- Cardiovascular Medicine
- Infectious Diseases
- Radiology
Background:
- Mycotic aneurysms, infections of the aorta, are rare, often caused by Staphylococcus or Salmonella.
- Emphysematous aortitis, a severe complication, involves gas in the aortic wall, leading to high mortality.
- It typically arises from infection on pre-damaged aortic endothelium, common in atherosclerosis.
Observation:
- A 66-year-old male with comorbidities presented with tachycardia and tachypnea.
- Chest CT revealed thoracic aortic inflammation with gas bubbles along the aortic wall.
- Post-mortem cultures identified Clostridium innocuum as the causative agent.
Findings:
- The case presents a unique instance of emphysematous aortitis due to Clostridial infection.
- Radiographic findings, though rare, are highly characteristic of the condition.
- Clostridium innocuum was identified as the specific pathogen in this thoracic aortic infection.
Implications:
- Emphysematous aortitis, while rare, requires immediate and aggressive clinical management.
- Characteristic imaging findings are crucial for early diagnosis and intervention.
- Understanding causative agents like Clostridium innocuum aids in targeted treatment strategies.
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Aneurysm I: Introduction
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm III: Interprofessional Care
Rheumatic Heart Disease I: Introduction
Myocarditis I: Introduction
Mitral Stenosis I: Introduction

