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Published on: April 1, 2022
The Use of Radial Artery for CABG: An Update
Francesco Nappi1, Francesca Bellomo2, Pierluigi Nappi2
1Department of Cardiac Surgery, Centre Cardiologique du Nord de Saint-Denis, Paris, France.
Insights
The radial artery is a safe and effective graft for coronary artery bypass grafting, showing superior patency rates compared to vein grafts. It is the preferred conduit after the internal thoracic artery for coronary operations.
Area of Science:
- Cardiovascular Surgery
- Vascular Grafting
- Cardiac Surgery Research
Background:
- The radial artery has been utilized as a secondary conduit for coronary artery bypass grafting (CABG) since 1971.
- Previous clinical studies on radial artery grafts were underpowered, leading to inconclusive outcome data.
- With nearly 50 years of experience, a comprehensive review is needed to establish its optimal role.
Purpose of the Study:
- To review existing literature and define the best alternative conduit for CABG after the left internal thoracic artery.
- To evaluate the efficacy and safety of the radial artery as a secondary or tertiary conduit in CABG.
- To compare radial artery graft outcomes with other available conduits, particularly saphenous vein grafts.
Main Methods:
- A thorough literature review was conducted, focusing on randomized controlled trials, propensity-matched observational studies, and meta-analyses.
- Data from a large patient population receiving arterial conduits and saphenous vein grafts were analyzed.
- Studies comparing clinical outcomes and graft patency rates were prioritized.
Main Results:
- The radial artery demonstrates safety and effectiveness as a secondary CABG conduit.
- Graft patency and clinical outcomes are superior when using the radial artery compared to saphenous vein grafts.
- The radial artery is also effective as a third conduit, particularly for the right coronary artery territory.
Conclusions:
- The radial artery is a safe and effective alternative conduit for coronary artery bypass grafting.
- Radial artery grafts offer superior patency and outcomes compared to saphenous vein grafts.
- The aorto-to-coronary radial artery bypass graft is the conduit of choice following the left internal thoracic artery graft in CABG procedures.
Abstract:
We used the radial artery as a second target conduit for coronary artery bypass grafting since 1971. However, randomized clinical studies have demonstrated differences in clinical outcomes between the radial artery and other grafts because these trials are underpowered. As we proceed toward 50 years of experience with radial artery grafting, we examined the literature to define the best second-best target vessel for coronary artery bypass grafting. The literature was reviewed with emphasis, and a large number of randomized controlled trials, propensity-matched observational series, and meta-analyses were identified with a large patient population who received arterial conduit and saphenous vein grafts. The radial artery has been shown to be effective and safe when used as a second target conduit for coronary artery bypass grafting. Results and patency rates were superior to those for saphenous vein grafting. It has also been shown that the radial artery is a safe and effective graft as a third conduit into the territory of the artery right coronary artery. However, there is little evidence based on a few comparable series limiting the use of the gastroepiploic artery. In its fifth decade of use, we can finally deduced that the aorto-to-coronary radial bypass graft is the conduit of choice for coronary operations after the left internal thoracic artery to the left anterior descending artery.
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