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Balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension

Kyoko Hirakawa1, Eiichiro Yamamoto2, Seiji Takashio2

  • 1Department of Cardiovascular Medicine, Faculty of Life Science, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan. kyoko-h@kumamoto-u.ac.jp.

Cardiovascular Intervention and Therapeutics
|April 30, 2021
PubMed

Insights

Chronic thromboembolic pulmonary hypertension (CTEPH) treatments like pulmonary endarterectomy and balloon pulmonary angioplasty (BPA) improve patient outcomes. This review covers advances in CTEPH imaging, surgical, and interventional techniques for better hemodynamics and survival.

Area of Science:

  • Cardiology
  • Pulmonology
  • Interventional Radiology

Background:

  • Chronic thromboembolic pulmonary hypertension (CTEPH) results from pulmonary artery obstruction by blood clots.
  • Untreated CTEPH carries a poor prognosis, but established therapies improve hemodynamics and survival.

Purpose of the Study:

  • To review the evolving field of CTEPH.
  • To highlight advancements in imaging, surgical, and interventional treatments for CTEPH.

Main Methods:

  • Review of current literature on CTEPH therapies.
  • Discussion of imaging modalities, surgical techniques, and interventional procedures like BPA.

Main Results:

  • Pulmonary endarterectomy, BPA, and medical therapy have improved hemodynamics and right ventricular function in CTEPH patients.
  • BPA is a key therapy for inoperable CTEPH, though access is limited.

Conclusions:

  • Advances in CTEPH management, including imaging and interventions, have led to improved long-term survival.
  • Continued development in surgical and interventional techniques is crucial for managing CTEPH.

Keywords:
Balloon pulmonary angioplastyChronic thromboembolic pulmonary hypertension

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