Related Experiment Video
Updated: Nov 7, 2025
08:13
In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
19.8K
Subclinical hyperthyroidism: the cardiovascular point of view.
G Vidili1, A Delitala, R Manetti
1Department of Surgical, Medical and Experimental Sciences, University of Sassari, Sassari, Italy. aledelitala@uniss.it.
European Review for Medical and Pharmacological Sciences
|April 30, 2021
Summary
Subclinical hyperthyroidism (SHyper) is linked to cardiovascular issues like atrial fibrillation and heart failure. More research is needed to confirm these associations and assess treatment benefits.
Area of Science:
- Endocrinology
- Cardiology
- Geriatrics
Background:
- Subclinical hyperthyroidism (SHyper), characterized by low TSH with normal free thyroid hormones, is prevalent, especially in the elderly.
- SHyper is increasingly recognized for its potential health implications, particularly cardiovascular complications.
Purpose of the Study:
- To review the association between subclinical hyperthyroidism and cardiovascular conditions.
- To evaluate the evidence linking SHyper to atrial fibrillation, stroke, hypertension, heart failure, and mortality.
Main Methods:
- A literature search was conducted using PubMed and Google Scholar.
- Keywords included "subclinical hyperthyroidism", "Atrial fibrillation", "Ischemic stroke", "Hypertension", "Heart failure", and "Mortality".
Main Results:
- SHyper is associated with atrial fibrillation and potentially ischemic stroke, though the latter link is less definitive.
- The association with hypertension is uncertain. SHyper may increase the risk of acute heart failure, possibly due to rhythm disturbances.
- Limited data suggest a possible link between SHyper and mortality, likely due to cardiovascular effects.
Conclusions:
- Existing research highlights potential links between SHyper and cardiovascular issues like arrhythmias, heart failure, and stroke.
- Evidence supporting the benefits of treating SHyper remains insufficient.
Related Concept Videos
01:30Coronary Artery Disease III: Clinical Manifestations
116
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
116
01:30Hypertension III: Clinical Manifestations and Diagnostic Studies
169
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
169
01:29Hypertension II: Pathophysiology
291
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
291
01:27Psychoneuroimmunology: Cardiovascular Disease
144
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
144
01:26Coronary Artery Disease II: Pathophysiology
148
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
148
01:29Cardiomyopathy III: Hypertrophic Cardiomyopathy
117
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
117