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Mortality and critical conditions in COVID-19 patients at private hospitals: weekend effect?
J González-Gancedo1, I Morales-Cané, P M Rodríguez-Muñoz
1Department of Nursing, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain. n82mocai@uco.es.
Insights
Advanced age, high creatinine, and D-dimer levels are key factors associated with COVID-19 mortality. Patients admitted to the intensive care unit (ICU) also faced higher mortality risks.
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Epidemiology
Background:
- COVID-19 poses significant mortality risks, particularly for patients requiring intensive care.
- Identifying predictors of mortality is crucial for resource allocation and patient management during pandemics.
Purpose of the Study:
- To identify factors associated with mortality and intensive care unit (ICU) admission in COVID-19 patients.
- To analyze clinical and laboratory parameters influencing patient outcomes.
Main Methods:
- Retrospective observational study of 1987 COVID-19 patients.
- Analysis of clinical variables, laboratory parameters, Charlson, and Elixhauser comorbidity indices.
- Logistic regression and Kaplan-Meier survival analysis were employed.
Main Results:
- Mortality positively correlated with advanced age, elevated creatinine, D-dimer levels, and comorbidity scores.
- Higher creatinine and D-dimer levels, along with advanced age, were significantly associated with increased mortality.
- Patients admitted to the ICU had poorer survival outcomes.
Conclusions:
- Advanced age and elevated creatinine and D-dimer levels are significant predictors of mortality in COVID-19 patients.
- Timely management and optimized nursing care are essential for improving outcomes in pandemic situations.
- Understanding these factors aids in resource optimization during health crises.
Objective:
The aim of the study was to find factors associated with the mortality of admission to the intensive care unit (ICU) in patients with COVID-19.
Materials And Methods:
Retrospective observational study with a database of 1987 patients with COVID-19 who had attended the emergency department of a private hospital network between February 2020 and April 2020 were analyzed. Clinical variables and some laboratory parameters were studied. The Charlson and Elixhauser comorbidity indices were calculated. The dependent variables were mortality and admission to the ICU. A descriptive and correlational analysis was performed. Logistic regression models and Kaplan-Meier survival curves were established.
Results:
Positive correlations were observed between age, creatinine, and D-dimer levels, as well as with the scores obtained with the Charlson and Elixhauser indices. Differences in the levels of these parameters were also observed when analyzing variables such as mortality, sex or admission to the ICU. Mortality was associated with high creatinine and D-dimer levels and advanced age. Survival curves indicated longer survival in patients not admitted to the ICU, admitted to the hospital during the week, and in those with lower creatinine and D-dimer levels.
Conclusions:
Mortality in Spanish patients with COVID-19 admitted to private hospitals was associated with high creatinine and D-dimer levels and advanced age. Longer survival was obtained on weekdays. This study provides valuable information on the management and nursing care of these patients in order to optimize resources in pandemic situations.
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