[Gonococcal pharyngitis]
N A Gerasimova1, N P Evstigneeva1, Yu N Grekova1
1Ural Research Institute of Dermatovenerology and Immunopathology, Ekaterinburg, Russia.
Vestnik Otorinolaringologii
|April 30, 2021
Summary
This case study highlights oligosymptomatic pharyngitis caused by Neisseria gonorrhoeae. Molecular diagnostics are crucial for identifying this infection and preventing the spread of resistant gonorrhea strains.
Area of Science:
- Infectious Diseases
- Microbiology
- Molecular Diagnostics
Background:
- Neisseria gonorrhoeae can cause oligosymptomatic pharyngitis, a sexually transmitted infection.
- Extragenital forms of sexually transmitted infections pose diagnostic challenges.
- Antimicrobial resistance in Neisseria gonorrhoeae is a growing public health concern.
Observation:
- A clinical case of oligosymptomatic pharyngeal gonorrhea in a young, sexually active male is described.
- Molecular biological diagnostic methods demonstrated advantages in identifying localized gonococcal pharyngitis.
- Microflora analysis revealed resistance of non-pathogenic Neisseria species to cephalosporins.
Findings:
- Molecular diagnostics are superior for detecting oligosymptomatic Neisseria gonorrhoeae pharyngitis.
- Non-pathogenic Neisseria species exhibit resistance to third and fourth-generation cephalosporins.
- Mixed infections in the oropharynx complicate diagnosis and treatment.
Implications:
- Undiagnosed pharyngeal gonorrhea can act as a reservoir for resistant Neisseria gonorrhoeae.
- Otorhinolaryngologists and dermatovenereologists must consider gonococcal pharyngitis in differential diagnoses.
- Effective molecular diagnostics are essential for controlling intractable gonococcal infections and antimicrobial resistance.
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