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Related Concept Videos

Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
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Parkinson's Disease: Overview01:15

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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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Neural Regulation01:37

Neural Regulation

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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

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The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
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Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
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Nervous System01:21

Nervous System

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The nervous system coordinates body functions through its complex network of nerve cells, enabling sensation and movement. It is divided into two primary parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and the spinal cord. The brain acts as the body's control center, processing sensory information and coordinating responses. The spinal cord functions as a major signaling pathway for the brain and the rest of the body.
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Related Experiment Video

Updated: Nov 7, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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Neurological update: COVID-19.

A L Ren1, R J Digby1, E J Needham2

  • 1Division of Anaesthesia, University of Cambridge, Cambridge, UK.

Journal of Neurology
|April 30, 2021
PubMed
Summary
This summary is machine-generated.

Neurological complications of Coronavirus Disease 2019 (COVID-19) arise from cerebrovascular issues, immune responses, and critical illness effects. Direct nervous system invasion by SARS-CoV-2 is unlikely a major factor.

Keywords:
COVID-19Cerebrovascular diseaseCritical illnessNeuroimmunology

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Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic
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Area of Science:

  • Neurology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Coronavirus Disease 2019 (COVID-19), primarily a respiratory illness, presents with diverse neurological complications.
  • These complications have been observed since the early stages of the pandemic.
  • Understanding the mechanisms behind these neurological effects is crucial for patient management.

Purpose of the Study:

  • To review and synthesize current knowledge on the neurological complications of COVID-19.
  • To explore the primary pathophysiological mechanisms contributing to neurological damage in COVID-19 patients.
  • To assess the likelihood and significance of direct Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) neuroinvasion.

Main Methods:

  • Literature review of studies on COVID-19 and neurological complications.
  • Analysis of pathophysiological pathways including cerebrovascular disease, immune-mediated disorders, and critical illness effects.
  • Evaluation of evidence regarding direct viral invasion of the nervous system.

Main Results:

  • Major causes of neurological damage in COVID-19 include cerebrovascular events, immunologically mediated disorders, and critical illness sequelae.
  • Direct invasion of the nervous system by SARS-CoV-2 is considered unlikely to be a significant factor, despite ongoing uncertainty.
  • A comprehensive understanding of these mechanisms is evolving.

Conclusions:

  • Neurological complications are a significant aspect of the COVID-19 disease spectrum.
  • Cerebrovascular, immunological, and critical illness factors are the predominant drivers of neurological damage.
  • Further research is needed to fully elucidate the complex interplay between SARS-CoV-2 infection and the nervous system.