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The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity
Winston McCormick1, Leonard A Mermel2,3
1Warren Alpert Medical School of Brown University, 222 Richmond St, Providence, RI, 02903, USA.
Virology Journal
|May 1, 2021
Abstract:
The COVID-19 pandemic has brought more widespread attention to the basic reproductive number (Ro), an epidemiologic measurement. A lesser-known measure of virologic infectivity is the particle-to-plaque ratio (P:PFU). We suggest that comparison between the two parameters may assist in better understanding viral transmission dynamics.
