Evidence-based clinical practice guideline: Reconstruction after skin cancer resection

Area of Science:

• Dermatology
• Plastic Surgery
• Evidence-Based Medicine

Background:

• Skin cancer resection often requires complex reconstruction.
• Existing reconstructive techniques are diverse, leading to varied clinical approaches.
• A need exists for standardized, evidence-based guidelines for post-skin cancer surgery reconstruction.

Purpose of the Study:

• To establish consensus and develop evidence-based recommendations for reconstruction after skin cancer resection.
• To identify common principles applicable across different reconstructive techniques and clinical settings.
• To improve the quality of patient care through standardized management strategies.

Main Methods:

• Convened a multi-disciplinary work group with diverse stakeholder involvement.
• Conducted a systematic literature review to identify relevant scientific research.
• Utilized the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology for appraising evidence quality.

Main Results:

• Developed recommendations on key aspects of reconstruction: timing, anticoagulation, antibiotic use, pain control, and follow-up.
• Distinguished between office-based and facility-based treatment options where applicable.
• Identified areas where evidence was insufficient for high-level recommendations.

Conclusions:

• The guidelines provide a framework for managing reconstruction after skin cancer resection.
• Further methodologically robust studies are crucial to strengthen recommendations and guide clinical practice.
• Standardization of care can enhance patient outcomes in reconstructive surgery.