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The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
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CT-Based COVID-19 triage: Deep multitask learning improves joint identification and severity quantification.

Mikhail Goncharov1, Maxim Pisov2, Alexey Shevtsov3

  • 1Skolkovo Institute of Science and Technology, Moscow, Russia; Kharkevich Institute for Information Transmission Problems, Moscow, Russia.

Medical Image Analysis
|May 1, 2021
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Summary
This summary is machine-generated.

This study introduces a deep learning model for prioritizing COVID-19 (coronavirus disease 2019) CT scans and assessing disease severity. The multitask approach effectively identifies COVID-19 cases and quantifies lung involvement, aiding in timely patient care.

Keywords:
COVID-19Chest computed tomographyConvolutional neural networkTriage

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Area of Science:

  • Radiology
  • Computer Science
  • Artificial Intelligence

Background:

  • Healthcare systems, including radiology departments, are overloaded by the COVID-19 pandemic.
  • Existing deep learning methods for CT analysis have not directly addressed study triage.
  • Prioritizing COVID-19 cases and assessing severity are crucial for efficient patient management.

Purpose of the Study:

  • To develop a deep learning model for simultaneous identification of COVID-19 and severity quantification from CT scans.
  • To formalize study triage as a computer science problem, addressing both patient prioritization and care allocation.
  • To investigate a multitask approach for improved performance compared to single-task models.

Main Methods:

  • A convolutional neural network utilizing a multitask approach was proposed, integrating classification and severity estimation.
  • The model was trained on approximately 1500 public CT studies and validated on a diverse holdout dataset of 123 chest CT scans.
  • The classification layers were strategically applied to a spatially detailed feature map within the U-Net architecture.

Main Results:

  • The multitask model achieved high performance in identifying COVID-19, with ROC AUC scores of 0.87±0.01 (vs. bacterial pneumonia), 0.93±0.01 (vs. cancerous nodules), and 0.97±0.01 (vs. healthy controls).
  • Excellent performance was observed in severity quantification, achieving a 0.97±0.01 Spearman Correlation.
  • The proposed model outperformed existing single-task approaches in both identification and quantification tasks.

Conclusions:

  • The developed multitask deep learning model offers an effective solution for prioritizing COVID-19 CT studies and quantifying disease severity.
  • This approach can significantly aid in early patient isolation and directing severe cases to appropriate medical care.
  • The study highlights the benefit of a multitask strategy and specific architectural choices in deep learning for medical image analysis.