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Production of 52Mn using a semi-automated module
Jennifer M Pyles1, Adriana V F Massicano2, Jean-Pierre Appiah2
1Department of Radiology, The University of Alabama at Birmingham, Birmingham, AL, USA; Department of Chemistry, The University of Alabama at Birmingham, Birmingham, AL, USA.
Abstract:
This work focused on the production and purification of the positron emitter 52Mn (t1/2 = 5.6 d) via the natCr(p,n)52Mn reaction, using a TR24 cyclotron and a semi-automated system for the purification of 52Mn. Based on two-column and three-column systems, the recovery of 52Mn was 79.7 ± 6.2% (n = 3) and 70.8 ± 3.3% (n = 3), with processing times of 6.9 ± 0.5 h and 8.2 ± 0.6 h, respectively.
