Mortality Rate of Patients With COVID-19 Based on Underlying Health Conditions

Won-Young Choi1

  • 1Division of Interdisciplinary Industrial Studies, Hanyang University, Seoul, Republic of Korea.

Insights

Patients with underlying health conditions had a 4x higher mortality rate from coronavirus disease (COVID-19). Male sex, older age, and comorbidities significantly increased death risk, especially in older males with underlying diseases.

Area of Science:

  • Epidemiology
  • Public Health
  • Infectious Diseases

Background:

  • Coronavirus disease (COVID-19) poses a significant global health threat.
  • Understanding mortality risk factors is crucial for effective patient management and resource allocation.

Purpose of the Study:

  • To evaluate COVID-19 mortality rates based on sex, age, and underlying health conditions.
  • To determine if underlying diseases offer prognostic value for COVID-19-related death.

Main Methods:

  • Conditional probability was used to assess mortality rates.
  • Multivariable logistic regression analysis estimated adjusted odds ratios (ORs).

Main Results:

  • Patients with underlying health conditions had a 12% mortality rate, 4 times higher than those without.
  • Mortality rates for women and men with underlying conditions were 5.5 and 3.4 times higher, respectively.
  • Male sex (OR: 1.83), age ≥ 41 years (ORs > 2.70), and underlying conditions (OR: 2.20) were significant risk factors for death.

Conclusions:

  • Older patients with underlying diseases and male patients with underlying diseases face a significantly higher probability of death.
  • Targeted attention and interventions are warranted for these high-risk populations.
  • Underlying health conditions are a critical prognostic indicator for COVID-19 mortality.
Abstract

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.0K
Actuarial Approach01:20

Actuarial Approach

The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
175
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
450
Chronic Obstructive Pulmonary Disease01:22

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.8K
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.1K
Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
4.7K