Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

532
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
532
Modeling in Therapy01:26

Modeling in Therapy

218
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
218

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Factors Associated With the Rising Trend in Self-Reported Cognitive Disability Among U.S. Adults Aged 18-39 From 2013-2024.

Annals of clinical and translational neurology·2026
Same author

A Scoping Review on Positive Emotions and Affect in Autism.

Journal of autism and developmental disorders·2026
Same author

Altered aperiodic EEG spectral power during speech perception task is associated with verbal communication in youths with Autism Spectrum Disorder.

Scientific reports·2026
Same author

A longitudinal investigation of aggression and social skills in autistic youth.

Research in autism·2026
Same author

Optimizing functional connectivity scanning conditions for predicting autistic traits.

Nature. Mental health·2026
Same author

Are Differences in Social Drive in Childhood and Adolescence Diagnosis Specific? A Multimeasurement Subtyping Approach.

JAACAP open·2026

Related Experiment Video

Updated: Nov 7, 2025

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers
09:16

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Published on: March 14, 2018

10.5K

Refining biomarker evaluation in ASD.

James C McPartland1

  • 1Professor of Child Psychiatry and Psychology, Yale Child Study Center, 230 South Frontage Road, New Haven, CT 06520, United States.

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology
|May 3, 2021
PubMed
Summary
This summary is machine-generated.

This commentary discusses reasonable biomarker expectations for autism spectrum disorder (ASD). It emphasizes defining the objective and evaluating biomarkers against best practices for ASD research and clinical use.

Keywords:
Autism spectrum disorderBiomarkersClinical trialsEndpoints

More Related Videos

Strategies for Assessing Autistic-Like Behaviors in Mice
07:38

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

1.6K
An Electrophysiology Protocol to Measure Reward Anticipation and Processing in Children
05:04

An Electrophysiology Protocol to Measure Reward Anticipation and Processing in Children

Published on: October 4, 2018

7.2K

Related Experiment Videos

Last Updated: Nov 7, 2025

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers
09:16

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Published on: March 14, 2018

10.5K
Strategies for Assessing Autistic-Like Behaviors in Mice
07:38

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

1.6K
An Electrophysiology Protocol to Measure Reward Anticipation and Processing in Children
05:04

An Electrophysiology Protocol to Measure Reward Anticipation and Processing in Children

Published on: October 4, 2018

7.2K

Area of Science:

  • Neuroscience
  • Genetics
  • Biochemistry

Background:

  • Autism spectrum disorder (ASD) presents complex diagnostic and therapeutic challenges.
  • Biomarkers are crucial for advancing objective measures in ASD research.
  • Current biomarker development in ASD requires clear definitions and rigorous evaluation.

Purpose of the Study:

  • To define what constitutes a biomarker in the context of ASD.
  • To outline the requirements for developing valid ASD biomarkers.
  • To explore the potential utility of biomarkers in ASD.

Main Methods:

  • This is a commentary, not an empirical study.
  • It involves a conceptual analysis of biomarker definitions and requirements.
  • The approach addresses key questions regarding ASD biomarkers.

Main Results:

  • A clear definition of a biomarker is essential for ASD research.
  • Rigorous criteria are needed to validate biomarkers for ASD.
  • Biomarkers can be useful if their objectives and evaluations align with best practices.

Conclusions:

  • Establishing clear objectives for ASD biomarkers is paramount.
  • Evaluating biomarkers against current best practices ensures their relevance and utility.
  • A structured approach to biomarker development will facilitate progress in ASD.