Related Experiment Videos
Synthesis of p-menthane derivatives with potential biological activity
K Witkiewicz1, Z Rykowski, Z Machoń
1Department of Organic Chemistry, Faculty of Pharmacy Medical Academy, Wrocław, Poland.
Die Pharmazie
|February 1, 1988
Abstract:
The synthesis of amino ketones and amino alcohols in p-menthane series is presented. These compounds were obtained in Mannich reaction, starting from the unsaturated ketone p-mentha-6,8-dien-2-one and its saturated analogue p-menthan-2-one. The structures of the compounds obtained were established by means of chemical transformations and elemental and spectral (IR, 1H NMR) analysis. The compounds obtained were subjected to the pharmacological investigations.