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Rectovaginal fistula in a cervical cancer patient treated with sequential radiotherapy and bevacizumab: A dose-volume
Kento Tomizawa1, Ken Ando1, Hirofumi Shimada2
1Department of Radiation Oncology Gunma University Graduate School of Medicine Gunma Japan.
Clinical Case Reports
|May 3, 2021
Abstract:
Bevacizumab is a monoclonal antibody against vascular endothelial growth factor that exerts antitumor effect by preventing tumor angiogenesis. Gastrointestinal fistula is a common side effect of bevacizumab in combination with radiotherapy. This case of rectovaginal fistula indicates that the side effect may be unpredictable by the conventional dose-volume parameters for the rectum.

