Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Orphaned Innovation: Cost, Structural Barriers, and Global System Shifts Prompting Reimbursement Reform in Endoscopic Spine Surgery-Insights From 1.2 Million Cases.

International journal of spine surgery·2026

Same author

Defining spine care: a framework for scope, standards, and bidirectional care transitions.

Journal of spine surgery (Hong Kong)·2026

Same author

Transforaminal Endoscopic Lumbar Decompression: Defining Its Scope and Limitations.

International journal of spine surgery·2026

Same author

Lumbar Spinal Endoscopy: Mature, Durable, and Established-Not Investigational.

International journal of spine surgery·2026

Same author

The Future of Endoscopic Spine Surgery in the United States: Lifeline or Liability?

International journal of spine surgery·2026

Same author

ISASS Brave New Continuing Medical Education World: The Stifling of Innovation in Spine Surgery Through Overrestriction of Collaboration.

International journal of spine surgery·2026

Search research articles

Related Experiment Video

Updated: Nov 7, 2025

Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model

Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model

Published on: February 10, 2023

AGENT ORANGE-INDUCED Anaplastic Large-Cell Lymphoma (ALCL) with Cutaneous Involvement.

Morgan Lorio¹, Brandon Lewis², John Hoy³

¹Advanced Orthopedics Altamonte Springs FL USA.

Clinical Case Reports

|May 3, 2021

Summary

This summary is machine-generated.

We report a rare case of Agent Orange-induced Anaplastic Large-Cell Lymphoma (ALCL) affecting the hand. This study details the surgical removal and subsequent treatment of this unusual presentation.

Keywords:

Dermatology Oncology Orthopaedics

More Related Videos

Author Spotlight: Advancing the Detection of Low-Frequency Mutations in Cancer Tissues

Author Spotlight: Advancing the Detection of Low-Frequency Mutations in Cancer Tissues

Published on: August 23, 2024

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood

Published on: February 1, 2013

Related Experiment Videos

Last Updated: Nov 7, 2025

Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model

Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model

Published on: February 10, 2023

Author Spotlight: Advancing the Detection of Low-Frequency Mutations in Cancer Tissues

Author Spotlight: Advancing the Detection of Low-Frequency Mutations in Cancer Tissues

Published on: August 23, 2024

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood

Published on: February 1, 2013

Area of Science:

Oncology
Dermatology
Toxicology

Background:

Anaplastic Large-Cell Lymphoma (ALCL) is a CD30-positive lymphoproliferative neoplasm.
Skin involvement is a known, though less common, manifestation of ALCL.
Agent Orange exposure has been linked to various cancers.

Observation:

A rare case of ALCL with significant cutaneous involvement of the hand was observed.
The patient's condition was suspected to be induced by Agent Orange exposure.
The lesion presented as a distinct manifestation on the hand.

Findings:

Surgical excision was performed as a primary treatment modality.
The case highlights a unique presentation of ALCL secondary to Agent Orange exposure.
Successful follow-up treatment was administered post-surgery.

Implications:

This case expands the understanding of ALCL's potential etiologies and clinical presentations.
It underscores the importance of considering environmental exposures, such as Agent Orange, in lymphoproliferative disorders.
Highlights the need for vigilance in diagnosing and managing cutaneous manifestations of ALCL, especially in exposed populations.