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Related Concept Videos

Anatomy of the Ear01:16

Anatomy of the Ear

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Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
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Surgical Treatment of an Endolymphatic Sac Tumor
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Lymphoma Masquerading as an Ear Mass.

Karen N Cuartas1, Nathaniel R Wilson1, Jaya Kala1

  • 1Internal Medicine, University of Texas Health Science Center at Houston, Houston, USA.

Cureus
|May 3, 2021
PubMed
Summary
This summary is machine-generated.

Diffuse large B-cell lymphoma (DLBCL) rarely presents as an ear mass. This case highlights a 38-year-old male with DLBCL manifesting as an ear lesion, emphasizing diagnostic challenges and potential for delayed systemic disease detection.

Keywords:
clinical case reportdelayed diagnosisdiffuse large b cell lymphomaear neoplasmincidental findingnon-hodgkin lymphoma

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Area of Science:

  • Oncology
  • Hematology
  • Pathology

Background:

  • Malignancies of the ear are infrequently reported and often misdiagnosed.
  • Diffuse large B-cell lymphoma (DLBCL) is a common non-Hodgkin lymphoma, but its presentation as an ear mass is exceptionally rare in medical literature.

Observation:

  • A 38-year-old male presented with a four-month history of worsening dyspnea and cough.
  • Physical examination revealed a significant erythematous, non-tender, immobile mass in the right lower ear, specifically the intertragic notch.
  • Imaging studies (CT neck and chest) demonstrated enlarged cervical lymph nodes and extensive mediastinal, pulmonary, pleural, and pericardial soft tissue involvement.

Findings:

  • Biopsy of the ear mass confirmed DLBCL, germinal center B-type.
  • The patient's symptoms of dyspnea and cough were associated with widespread DLBCL infiltration.

Implications:

  • This case underscores the importance of considering rare presentations for hematologic malignancies.
  • Prompt radiological evaluation of persistent respiratory symptoms, even in the presence of an unusual ear mass, is crucial for early diagnosis and management of systemic disease.
  • Timely diagnosis could potentially mitigate extensive disease spread and reduce patient morbidity.